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The present study confirmed that the WT1 gene was alternatively spliced at Ex4a to create isoforms with opposing roles in apoptosis, anti-apoptotic isoforms (key WT1 isoforms) and pro-apoptotic isoform (truncated Ex4a(+)WT1 isoform). A number of other genes involved in apoptosis, this sort of as p53 [39], Survivin [40], Fas [41], and caspase-9 [42] are recognized to produce isoforms with opposing
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List of Prime BE/ Colleges In India based on 2017 Ranking. The methodology for rankings stay the identical like final time. In is equivalent to IIT's&IIM' least much better than several NIT's.